Maternal Lipids at 28 Weeks' Gestation and Offspring Adiposity at Age 5 to 7 Years.

ABSTRACT:

Context

Obesity is a global epidemic, and there is a focus on identifying markers of obesity in children with a view to prevention.

Objective

We aimed to examine prospectively the association of maternal fasting lipids with adiposity in 5- to 7-year-old offspring in a large observational study.

Design

Pregnant women (1612) were recruited to the Belfast center of the Hyperglycemia and Adverse Pregnancy Outcome study in a large tertiary maternity hospital at an average of 28 weeks' gestation. Maternal fasting total cholesterol, low-density lipoprotein-cholesterol, triglycerides, and high-density lipoprotein-cholesterol were estimated at 28 weeks' gestation. Offspring-mother pairs (819) were included in the current study, and adiposity was expressed as body mass index (B

SUBMITTER: Thaware PK 

PROVIDER: S-EPMC6179179 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature