Small intra-individual variability of the pre-ejection period justifies the use of pulse transit time as approximation of the vascular transit.

ABSTRACT:

Background

Vascular transit time (VTT) is the propagation time of a pulse wave through an artery; it is a measure for arterial stiffness. Because reliable non-invasive VTT measurements are difficult, as an alternative we measure pulse transit time (PTT). PTT is defined as the time between the R-wave on electrocardiogram and arrival of the resulting pulse wave in a distal location measured with photoplethysmography (PPG). The time between electrical activation of the ventricles and the resulting pulse wave after opening of the aortic valve is called the pre-ejection period (PEP), a component of PTT. The aim of this study was to estimate the variability of PEP at rest, to establish how accurate PTT is as approximation of VTT.

Methods

PTT was measured and PEP was assessed with

SUBMITTER: Kortekaas MC 

PROVIDER: S-EPMC6179208 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature