Short-term effects of fine particulate matter and ozone on the cardiac conduction system in patients undergoing cardiac catheterization.

ABSTRACT:

Background

Air pollution-induced changes in cardiac electrophysiological properties could be a pathway linking air pollution and cardiovascular events. The evidence of air pollution effects on the cardiac conduction system is incomplete yet. We investigated short-term effects of particulate matter ≤ 2.5 μm in aerodynamic diameter (PM_2.5) and ozone (O₃) on cardiac electrical impulse propagation and repolarization as recorded in surface electrocardiograms (ECG).

Methods

We analyzed repeated 12-lead ECG measurements performed on 5,332 patients between 2001 and 2012. The participants came from the Duke CATHGEN Study who underwent cardiac catheterization and resided in North Carolina, United States (NC, U.S.). Daily concentrations of PM_2.5 and O

SUBMITTER: Zhang S 

PROVIDER: S-EPMC6180522 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature