Screening for Zika virus RNA in sera of suspected cases: a retrospective cross-sectional study.

ABSTRACT:

Background

Zika virus (ZIKV) became a global human health concern owing to its rapid spread worldwide and its association with congenital and neurological disorders. The current epidemiological profile of arboviruses in Brazil is characterized by widespread co-circulation of Dengue virus, Chikungunya virus, and ZIKV throughout the country. These viruses cause acute diseases frequently with overlapping symptoms, which could result in an inaccurate diagnosis based solely on clinical and epidemiological grounds. Here we conducted a screening for ZIKV RNA in serum samples from patients across Brazil with suspected ZIKV infection.

Methods

Using RT-qPCR, we investigated ZIKV RNA in 3001 serum samples. Samples were passively acquired through a private laboratory network, between De

SUBMITTER: Sacchetto L 

PROVIDER: S-EPMC6180573 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature