Management Strategies and Outcomes for Hyponatremia in Cirrhosis in the Hyponatremia Registry.

ABSTRACT:

Aim

Treatment practices and effectiveness in cirrhotic patients with hyponatremia (HN) in the HN Registry were assessed.

Methods

Characteristics, treatments, and outcomes were compared between patients with HN at admission and during hospitalization. For HN at admission, serum sodium concentration [Na] response was analyzed until correction to > 130 mmol/L, switch to secondary therapy, or discharge or death with sodium ≤ 130 mmol/L.

Results

Patients with HN at admission had a lower [Na] and shorter length of stay (LOS) than those who developed HN (P < 0.001). Most common initial treatments were isotonic saline (NS, 36%), fluid restriction (FR, 33%), and no specific therapy (NST, 20%). Baseline [Na] was higher in patients treated with NST, FR, or NS versus hyper

SUBMITTER: Sigal SH 

PROVIDER: S-EPMC6180997 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature