Prevalence of hypothyroidism in patients with hyponatremia: A retrospective cross-sectional study.

ABSTRACT:

Objective

Hypothyroidism has been suggested to be an uncommon cause of hyponatremia. However, little is known about the prevalence of hypothyroidism in patients with different levels of hyponatremia. The objective of this study was to investigate the prevalence of hypothyroidism among patients with hyponatremia of varying severity while taking into consideration potential confounders associated with thyroid function.

Methods

All data on thyrotropin (TSH), free thyroxine (T4), and serum sodium (Na) levels were retrospectively collected from medical records at two Japanese tertiary hospitals. The main outcome measure was overt hypothyroidism, defined as TSH > 10.0 μIU/mL and free T4 < 1.01 ng/dL.

Results

Of 71,817 patients, 964 patients (1.3%) had overt hypothyroidism.

SUBMITTER: Nagata T 

PROVIDER: S-EPMC6181416 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature