Problems to affect long-term survival for breast cancer patients: An observational study of subsequent lung/bronchus malignancies.

ABSTRACT: The overall survival of breast cancer (BC) patients increased significantly for decades; however, their long-term survival was seriously impaired by subsequent malignancies. This study aimed to investigate the risk factors of subsequent lung / bronchus primary malignancies among BC survivors.A total of 535,941 BC female survivors diagnosed were identified by using SEERStat database in 1973 to 2014. Among them, 9398 had subsequent lung/bronchus malignancies. Clinico-pathological risk factors were evaluated for the development of subsequent lung/bronchus cancer. The main measures were the incidence and risk factors of subsequent lung/bronchus primaries. Logistic regression analysis and survival analysis were performed.Overall, among 535,941 BC survivors, 73,394 (13.69%) patients with subsequ

SUBMITTER: Liu J 

PROVIDER: S-EPMC6181575 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature