Influence of lung function and sleep-disordered breathing on stroke: a community-based study.

ABSTRACT:

Background and purpose

Impaired lung function is regarded as a risk factor for stroke in patients with chronic obstructive pulmonary disease. However, the association between reduced lung function and incident stroke in a community-based population with sleep-disordered breathing (SDB) remains unknown.

Methods

A prospective study was performed within the Sleep Heart Health Study cohort. Full montage home sleep testing and spirometry data on 2082 and 2072 individuals with and without SDB, respectively, were analysed. Cox proportional hazards regression models were used to estimate the association between lung function and incident stroke.

Results

Over 11.7 years, 183 cases of stroke were identified in participants without pre-existing cardiovascular diseases, including

SUBMITTER: Zhang J 

PROVIDER: S-EPMC6181793 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature