Trends in the use of prenatal testing services for fetal aneuploidy in Ontario: a descriptive study.

ABSTRACT:

Background

In 2014, Ontario augmented its publicly funded multiple-marker screening program for prenatal aneuploidy by incorporating cell-free fetal DNA (cffDNA) analysis for high-risk pregnancies. We assessed trends in the use of multiple-marker screening, cffDNA screening and prenatal diagnostic testing before and after implementation of public funding.

Methods

We conducted a descriptive study based on data from the Better Outcomes Registry & Network (BORN) Ontario. The study population included all pregnant women in Ontario with a singleton pregnancy and an expected date of delivery between July 1, 2012, and Mar. 31, 2016, with pregnancy data captured in BORN. Pregnancy losses and terminations before 20 weeks' gestation not captured in BORN were excluded. We generated des

SUBMITTER: Huang T 

PROVIDER: S-EPMC6182116 | biostudies-literature | 2018 Oct-Dec

REPOSITORIES: biostudies-literature