Urinary creatinine excretion is related to short-term and long-term mortality in critically ill patients.

ABSTRACT:

Purpose

Patients with reduced muscle mass have a worse outcome, but muscle mass is difficult to quantify in the ICU. Urinary creatinine excretion (UCE) reflects muscle mass, but has not been studied in critically ill patients. We evaluated the relation of baseline UCE with short-term and long-term mortality in patients admitted to our ICU.

Methods

Patients who stayed ≥ 24 h in the ICU with UCE measured within 3 days of admission were included. We excluded patients who developed acute kidney injury stage 3 during the first week of ICU stay. As muscle mass is considerably higher in men than women, we used sex-stratified UCE quintiles. We assessed the relation of UCE with both in-hospital mortality and long-term mortality.

Results

From 37,283 patients, 6151 patients with

SUBMITTER: Hessels L 

PROVIDER: S-EPMC6182361 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature