Current and Innovative Pharmacological Options to Treat Typical and Atypical Trigeminal Neuralgia.

ABSTRACT: Trigeminal neuralgia is a representative neuropathic facial pain condition, characterised by unilateral paroxysmal pain in the distribution territory of one or more divisions of the trigeminal nerve, triggered by innocuous stimuli. A subgroup of patients with trigeminal neuralgia [TN (previously defined as atypical TN)] also suffer from concomitant continuous pain, i.e. a background pain between the paroxysmal attacks. The aim of this review is to provide current, evidence-based, knowledge about the pharmacological treatment of typical and atypical TN, with a specific focus on drugs in development. We searched for relevant papers within PubMed, EMBASE, the Cochrane Database of Systematic Reviews and the Clinical Trials database (ClinicalTrials.gov), taking into account publications up to F

SUBMITTER: Di Stefano G 

PROVIDER: S-EPMC6182468 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature