Multidrug resistant Pseudomonas aeruginosa in Estonian hospitals.

ABSTRACT:

Background

We aimed to identify the main spreading clones, describe the resistance mechanisms associated with carbapenem- and/or multidrug-resistant P. aeruginosa and characterize patients at risk of acquiring these strains in Estonian hospitals.

Methods

Ninety-two non-duplicated carbapenem- and/or multidrug-resistant P. aeruginosa strains were collected between 27th March 2012 and 30th April 2013. Clinical data of the patients was obtained retrospectively from the medical charts. Clonal relationships of the strains were determined by whole genome sequencing and analyzed by multi-locus sequence typing. The presence of resistance genes and beta-lactamases and their origin was determined. Combined-disk method and PCR was used to evaluate carbapenemase and metallo-beta-lactamas

SUBMITTER: Telling K 

PROVIDER: S-EPMC6182868 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature