Coronary artery calcium quantification using contrast-enhanced dual-energy computed tomography scans in comparison with unenhanced single-energy scans.

ABSTRACT: Extracting coronary artery calcium (CAC) scores from contrast-enhanced computed tomography (CT) images using dual-energy (DE) based material decomposition has been shown feasible, mainly through patient studies. However, the quantitative performance of such DE-based CAC scores, particularly per stenosis, is underexamined due to lack of reference standard and repeated scans. In this work we conducted a comprehensive quantitative comparative analysis of CAC scores obtained with DE and compare to conventional unenhanced single-energy (SE) CT scans through phantom studies. Synthetic vessels filled with iodinated blood mimicking material and containing calcium stenoses of different sizes and densities were scanned with a third generation dual-source CT scanner in a chest phantom using a DE coro

SUBMITTER: Li Q 

PROVIDER: S-EPMC6183065 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature