Intraocular Photobonding to Enable Accommodating Intraocular Lens Function.

ABSTRACT:

Purpose

Accommodating intraocular lenses (A-IOLs) require capturing the ciliary muscle forces. Prior work demonstrated strong photo-initiated bonding between strips of capsular bag and poly(2-hydroxyethyl methacrylate); (pHEMA) polymer in an extraocular setting. We demonstrate that photobonding can be achieved intraocularly.

Methods

Phacoemulsification was performed in porcine eyes (<24 hours postmortem). A commercial intraocular lens (IOL; pHEMA-MMA material) was inserted in the capsular bag. Surface contact between the lens and capsular bag was ensured by continuous air infusion into the anterior chamber of the eye, which provided sufficient pressure at the interface, as well as oxygen. The capsular bag and IOL then were stained with 0.1% photosensitizer Rose Bengal (RB) s

SUBMITTER: Alejandre-Alba N 

PROVIDER: S-EPMC6183327 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature