The prognostic value of prognostic nutritional index in hepatocellular carcinoma patients: A meta-analysis of observational studies.

ABSTRACT:

Background and aims

The clinical value of the prognostic nutritional index (PNI) in hepatocellular carcinoma (HCC) has been investigated in previous studies, but the results remain controversial. Here we present a meta-analysis to systematically review the association between PNI and HCC prognosis.

Method

PubMed, EMBASE, Web of Science databases were systematically searched to identify relevant studies. Data were abstracted independently by two reviewers. A meta-analysis was performed to determine the prognostic and clinic-pathological values of PNI in HCC patients. Odds ratios (ORs) and 95% confidence intervals (CIs) were extracted to estimate the association of PNI with survival and clinic-pathological characteristics, respectively.

Results

A total of eleven studies

SUBMITTER: Wang Z 

PROVIDER: S-EPMC6185720 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature