Dietary protein and changes in markers of cardiometabolic health across 20 years of follow-up in middle-aged Americans.

ABSTRACT:

Objective

Dietary protein plays a role in counteracting age-related muscle loss. However, limited long-term data exist on protein intake and markers of cardiometabolic health, which tend to deteriorate with age.

Design

Prospective cohort study. FFQ-derived protein intake (g/d) and cardiometabolic markers were assessed up to five times across 20 years. Markers included systolic (SBP) and diastolic (DBP) blood pressures, circulating lipids (total, HDL and LDL cholesterol; TAG), estimated glomerular filtration rate (eGFR), fasting glucose (FG), weight and waist circumference (WC). Mixed models accounting for repeated measures were used to estimate adjusted mean annualized changes in outcomes per quartile category of protein.

Setting

Framingham Heart Study Offspring cohor

SUBMITTER: Hruby A 

PROVIDER: S-EPMC6185746 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature