Omega-3 fatty acids, membrane remodeling and cancer prevention.

ABSTRACT: Proteins are often credited as the macromolecule responsible for performing critical cellular functions, however lipids have recently garnered more attention as our understanding of their role in cell function and human health becomes more apparent. Although cellular membranes are the lipid environment in which many proteins function, it is now apparent that protein and lipid assemblies can be organized to form distinct micro- or nanodomains that facilitate signaling events. Indeed, it is now appreciated that cellular function is partly regulated by the specific spatiotemporal lipid composition of the membrane, down to the nanosecond and nanometer scale. Furthermore, membrane composition is altered during human disease processes such as cancer and obesity. For example, an increased rate of

SUBMITTER: Fuentes NR 

PROVIDER: S-EPMC6185832 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature