Parental experience modifies the Mimulus methylome.

ABSTRACT:

Background

Transgenerational plasticity occurs when the environmental experience of an organism modifies the growth and development of its progeny. Leaf damage in Mimulus guttatus exhibits transgenerational plasticity mediated through differential expression of hundreds of genes. The epigenetic mechanisms that facilitate this response have yet to be described.

Results

We performed whole genome bisulfite sequencing in the progeny of genetically identical damaged and control plants and developed a pipeline to compare differences in the mean and variance of methylation between treatment groups. We find that parental damage increases the variability of CG and CHG methylation among progeny, but does not alter the overall mean methylation. Instead it has positive effects in some r

SUBMITTER: Colicchio JM 

PROVIDER: S-EPMC6186029 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature