Potential drug-drug interactions in outpatient department of a tertiary care hospital in Pakistan: a cross-sectional study.

ABSTRACT:

Background

Potential drug-drug interactions (pDDIs) are one of the preventable drug related problems having the risk of serious adverse events or therapeutic failure. In developing countries like Pakistan, this issue remains poorly addressed. The objective of this study was to explore prevalence of pDDIs in the Outpatient Department (OPD) of a tertiary care hospital in Pakistan. The secondary aim was to describe the levels of reported pDDIs and develop a list of widespread clinically relevant interactions.

Methods

Prescriptions of 2400 OPD patients were analyzed for pDDIs through Micromedex Drug-Reax®. Prevalence, severity- and documentation-levels and widespread clinically relevant interactions were reported.

Results

Of total 2400 prescriptions, pDDIs were present in

SUBMITTER: Ismail M 

PROVIDER: S-EPMC6186060 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature