Intermittent bolus feeding promotes greater lean growth than continuous feeding in a neonatal piglet model.

ABSTRACT:

Background

Orogastric tube feeding is indicated in neonates with an impaired ability to ingest food normally and can be administered with an intermittent bolus or continuous feeding schedule.

Objectives

The objectives were to 1) compare the long-term effect of continuous with intermittent feeding on growth using the newborn pig as a model, 2) determine whether feeding frequency alters lean tissue and fat mass gain, and 3) identify the signaling mechanisms by which protein deposition is controlled in skeletal muscle in response to feeding frequency.

Design

Neonatal pigs were fed the same amount of a balanced formula by orogastric tube either as an intermittent bolus meal every 4 h (INT) or as a continuous infusion (CON). Body composition was assessed at the start and e

SUBMITTER: El-Kadi SW 

PROVIDER: S-EPMC6186212 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature