Conductively coupled flexible silicon electronic systems for chronic neural electrophysiology.

ABSTRACT: Materials and structures that enable long-term, intimate coupling of flexible electronic devices to biological systems are critically important to the development of advanced biomedical implants for biological research and for clinical medicine. By comparison with simple interfaces based on arrays of passive electrodes, the active electronics in such systems provide powerful and sometimes essential levels of functionality; they also demand long-lived, perfect biofluid barriers to prevent corrosive degradation of the active materials and electrical damage to the adjacent tissues. Recent reports describe strategies that enable relevant capabilities in flexible electronic systems, but only for capacitively coupled interfaces. Here, we introduce schemes that exploit patterns of highly doped si

SUBMITTER: Li J 

PROVIDER: S-EPMC6187144 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature