Micropipette-Based Microfluidic Device for Monodisperse Microbubbles Generation.

ABSTRACT: Microbubbles have various applications including their use as carrier agents for localized delivery of genes and drugs and in medical diagnostic imagery. Various techniques are used for the production of monodisperse microbubbles including the Gyratory, the coaxial electro-hydrodynamic atomization (CEHDA), the sonication methods, and the use of microfluidic devices. Some of these techniques require safety procedures during the application of intense electric fields (e.g., CEHDA) or soft lithography equipment for the production of microfluidic devices. This study presents a hybrid manufacturing process using micropipettes and 3D printing for the construction of a T-Junction microfluidic device resulting in simple and low cost generation of monodisperse microbubbles. In this work, microbubbl

SUBMITTER: Toshiyuki Matsumi C 

PROVIDER: S-EPMC6187383 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature