Validation of lung density indices by cardiac CT for quantification of lung emphysema.

ABSTRACT:

Objectives

Cardiovascular disease is often associated with COPD. Lung density quantification of images obtained from cardiac computed tomography (CT) scans would allow simultaneous evaluation of emphysema and coronary artery calcification score and provide further mechanistic insight into the relationship between these syndromes.

Patients and methods

We assessed the agreement between lung density indices obtained by cardiac and full-lung CT scans. Paired cardiac and chest CT scans were assessed in 156 individuals with and without airflow limitation. Quantitative threshold indices of low attenuation area (LAA) and 15th percentile density index (PD15) were compared in terms of precision using Spearman's correlation coefficient, accuracy using concordance correlation coefficien

SUBMITTER: Ronit A 

PROVIDER: S-EPMC6188118 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature