Clustering of Schizotypal Features in Unaffected First-Degree Relatives of Schizophrenia Patients.

ABSTRACT: Meehl conceptualized schizotypy as the phenotypic manifestations of a neural integrative defect resulting from a schizophrenia diathesis. The majority of schizotypy studies recruited subjects from the general population and revealed a multidimensional construct. This 2-phase investigation first examined the clustering of schizotypy in 194 unaffected relatives of schizophrenia patients using the Chapman Psychosis Proneness scales and then directly compared the cognitive profiles of negative schizotypal individuals and positive schizotypal individuals with schizophrenia patients and controls. In the first phase, cluster analysis categorized 194 unaffected relatives of schizophrenia patients into positive schizotypy (n = 33), negative schizotypy (n = 66), mixed schizotypy (n = 27), and low sc

SUBMITTER: Lui SSY 

PROVIDER: S-EPMC6188519 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature