Negative Schizotypy and Altered Functional Connectivity During Facial Emotion Processing.

ABSTRACT:

Background

Impairment in facial emotion perception is an important domain of social cognition deficits in schizophrenia. Although impaired facial emotion perception has been found in individuals with negative schizotypy (NS), little is known about the corresponding change in brain functional connectivity.

Methods

Sixty-four participants were classified into a high NS group (n = 34) and a low NS group (n = 30) based on their total scores on the Chapman scales for physical and social anhedonia. All participants undertook a facial emotion discrimination functional imaging task that consisted of four emotional valences (angry, fear, happy, and neutral). For univariate analysis, the signal change at the bilateral amygdala was compared for each emotional contrast using SPSS (P < .

SUBMITTER: Wang Y 

PROVIDER: S-EPMC6188525 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature