Proteomic analysis of four Clostridium botulinum strains identifies proteins that link biological responses to proteomic signatures.

ABSTRACT: Microorganisms alter gene and protein expression in response to environmental conditions to adapt and survive. Whereas the genetic composition of a microbe represents an organism's biological potential, the proteins expressed provide a functional readout of the organism's response to the environment. Understanding protein expression patterns in response to specific environmental conditions furthers fundamental knowledge about a microbe, which can be especially useful for understudied organisms such as Clostridium botulinum examined herein. In addition, protein expression patterns that reproducibly occur in certain growth conditions hold potential in fields such as microbial forensics, in which determination of conditions in which an unknown possible biothreat sample had been grown may be i

SUBMITTER: Deatherage Kaiser BL 

PROVIDER: S-EPMC6188780 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature