An observational study of environmental exposures, airway cytology, and performance in racing thoroughbreds.

ABSTRACT:

Background

Mild equine asthma is presumed to arise in response to environmental exposures but the relative impact of differing inflammatory phenotypes upon performance are largely unexplored.

Hypotheses

Airway inflammation negatively affects performance and cytological phenotype varies with environmental exposure.

Animals

Thoroughbred racehorses in active training and racing.

Methods

Thoroughbreds were recruited 24-48 hours before racing. Each horse was eligible for re-enrollment with each race entry. Within one hour of race completion, physical examination, respiratory endoscopy, and BAL were performed. Respirable and inhalable dust, respirable endotoxin, and respirable β-glucan exposures were measured at the breathing zone within one week after racing. Contro

SUBMITTER: Ivester KM 

PROVIDER: S-EPMC6189343 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature