Randomized placebo controlled clinical trial of an enteric coated micro-pelleted formulation of a pancreatic enzyme supplement in dogs with exocrine pancreatic insufficiency.

ABSTRACT:

Background

Pancreatic enzyme supplements for the treatment of exocrine pancreatic insufficiency (EPI) in dogs can be uncoated or enteric coated. Enteric coated supplements might be advantageous.

Hypothesis/objectives

Enteric coated enzyme supplements are superior to uncoated supplements in dogs with clinical EPI.

Animals

Eleven dogs with naturally occurring EPI that were apparently free from other diseases.

Methods

Randomized, blinded, controlled cross-over clinical trial comparing a novel micro-encapsulated enteric coated enzyme supplement to a commercially available uncoated product in dogs with clinical EPI. Search of serum canine serum trypsin-like immunoreactivity concentration ≤ 2.5 µg/L in the Gastrointestinal Laboratory database was used to identify dog

SUBMITTER: Parambeth JC 

PROVIDER: S-EPMC6189344 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature