Utility of C-reactive protein and serum amyloid A in the diagnosis of equine protozoal myeloencephalitis.

ABSTRACT:

Background

Accurate antemortem EPM diagnosis requires evidence of intrathecal antibody production. Some advocate the use of acute phase proteins in addition to serology, which alone results in substantial false positives.

Hypothesis/objectives

The purpose of this study was to determine if serum C-reactive protein (CRP) or serum amyloid A (SAA) concentrations were elevated in cases of equine protozoal myeloencephalitis (EPM) compared to other neurological diseases.

Animals

25 clinical cases of equine neurological disease: EPM (10), cervical vertebral stenotic myelopathy (CVSM) (10), neuroborreliosis (2), equine motor neuron disease (1), degenerative myelopathy (1), and leukoencephalomalacia (1).

Methods

Serum and CSF CRP and SAA were measured. Selection criteria

SUBMITTER: Mittelman NS 

PROVIDER: S-EPMC6189384 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature