Rapid Fabrication of Disposable Micromixing Arrays Using Xurography and Laser Ablation

ABSTRACT: We assessed xurography and laser ablation for the manufacture of passive micromixers arrays to explore the scalability of unconventional manufacture technologies that could be implemented under the restrictions of the Point of Care for developing countries. In this work, we present a novel split-and-recombine (SAR) array design adapted for interfacing standardized dispensing (handheld micropipette) and sampling (microplate reader) equipment. The design was patterned and sealed from A4 sized vinyl sheets (polyvinyl chloride), employing low-cost disposable materials. Manufacture was evaluated measuring the dimensional error with stereoscopic and confocal microscopy. The micromixing efficiency was estimated using a machine vision system for passive driven infusion provided by micropippetting

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PROVIDER: S-EPMC6189729 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature