Ontology highlight
ABSTRACT: Background
Little is known about potential harmful effects as a consequence of self-guided internet-based cognitive behaviour therapy (iCBT), such as symptom deterioration rates. Thus, safety concerns remain and hamper the implementation of self-guided iCBT into clinical practice. We aimed to conduct an individual participant data (IPD) meta-analysis to determine the prevalence of clinically significant deterioration (symptom worsening) in adults with depressive symptoms who received self-guided iCBT compared with control conditions. Several socio-demographic, clinical and study-level variables were tested as potential moderators of deterioration.Methods
Randomised controlled trials that reported results of self-guided iCBT compared with control conditions in adults with sy
SUBMITTER: Karyotaki E
PROVIDER: S-EPMC6190066 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature