A Method of Three-Dimensional Micro-Rotational Flow Generation for Biological Applications.

ABSTRACT: We report a convenient method to create a three-dimensional micro-rotational fluidic platform for biological applications in the direction of a vertical plane (out-of-plane) without contact in an open space. Unlike our previous complex fluidic manipulation system, this method uses a micro-rotational flow generated near a single orifice when the solution is pushed from the orifice by using a single pump. The three-dimensional fluidic platform shows good potential for fluidic biological applications such as culturing, stimulating, sorting, and manipulating cells. The pattern and velocity of the micro-rotational flow can be controlled by tuning the parameters such as the flow rate and the liquid-air interface height. We found that bio-objects captured by the micro-rotational flow showed self-

SUBMITTER: Yalikun Y 

PROVIDER: S-EPMC6190094 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature