Acoustic Manipulation of Bio-Particles at High Frequencies: An Analytical and Simulation Approach.

ABSTRACT: Manipulation of micro and nano particles in microfluidic devices with high resolution is a challenge especially in bioengineering applications where bio-particles (BPs) are separated or patterned. While acoustic forces have been used to control the position of BPs, its theoretical aspects need further investigation particularly for high-resolution manipulation where the wavelength and particle size are comparable. In this study, we used a finite element method (FEM) to amend analytical calculations of acoustic radiation force (ARF) arising from an imposed standing ultrasound field. First, an acoustic solid interaction (ASI) approach was implemented to calculate the ARF exerted on BPs and resultant deformation induced to them. The results were then used to derive a revised expression for th

SUBMITTER: Samandari M 

PROVIDER: S-EPMC6190359 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature