A Fluidic Interface with High Flow Uniformity for Reusable Large Area Resonant Biosensors.

ABSTRACT: Resonant biosensors are known for their high accuracy and high level of miniaturization. However, their fabrication costs prevent them from being used as disposable sensors and their effective commercial success will depend on their ability to be reused repeatedly. Accordingly, all the parts of the sensor in contact with the fluid need to tolerate the regenerative process which uses different chemicals (H₃PO₄, H₂SO₄ based baths) without degrading the characteristics of the sensor. In this paper, we propose a fluidic interface that can meet these requirements, and control the liquid flow uniformity at the surface of the vibrating area. We study different inlet and outlet channel configurations, estimating their performance using numerical simulations based on finite element method (FEM). Th

SUBMITTER: Azzopardi CL 

PROVIDER: S-EPMC6190451 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature