The association between blood pressure variability (BPV) with dementia and cognitive function: a systematic review and meta-analysis protocol.

ABSTRACT:

Background

A body of empirical work demonstrates that wide fluctuations in a person's blood pressure across consecutive measures, known as blood pressure variability (BPV), hold prognostic value to predict stroke and transient ischemic attack. However, the magnitude of association between BPV and other neurological outcomes remains less clear. This systematic review aims to pool together data regarding BPV with respect to incident dementia, cognitive impairment, and cognitive function.

Methods

Electronic databases (MEDLINE, EMBASE, and SCOPUS) will be searched for the key words blood pressure variability and outcomes of dementia, cognitive impairment, and cognitive function. Authors and reference lists of included studies will also be contacted to identify additional publish

SUBMITTER: VARIABLE BRAIN consortium 

PROVIDER: S-EPMC6190539 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature