Castleman's disease in the HIV-endemic setting.

ABSTRACT:

Introduction

Castleman's disease (CD), first described by Benjamin Castleman in 1954, is a giant or angiofollicular lymph node hyperplasia, described as a rare monotypic polyclonal B-cell lymphoproliferative disorder with an incompletely understood pathogenesis and variable clinical behavior. This study aimed to determine the incidence of CD diagnosis over an 11-year period. Additionally, the study aimed to describe the demographic, laboratory, and pathological features of CD.

Methods

This is a retrospective study where the demographic and laboratory data were retrieved from the Tygerberg Academic Hospital (TAH) patient electronic records and Tygerberg Lymphoma Study Group (TLSG) and statistical analysis performed on the patients diagnosed with CD.

Results

Fifty-four

SUBMITTER: Mahroug ER 

PROVIDER: S-EPMC6190808 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature