Association of Prenatal Maternal Depression and Anxiety Symptoms With Infant White Matter Microstructure.

ABSTRACT:

Importance

Maternal depression and anxiety can have deleterious and lifelong consequences on child development. However, many aspects of the association of early brain development with maternal symptoms remain unclear. Understanding the timing of potential neurobiological alterations holds inherent value for the development and evaluation of future therapies and interventions.

Objective

To examine the association between exposure to prenatal maternal depression and anxiety symptoms and offspring white matter microstructure at 1 month of age.

Design, setting, and participants

This cohort study of 101 mother-infant dyads used a composite of depression and anxiety symptoms measured in mothers during the third trimester of pregnancy and measures of white matter microstruc

SUBMITTER: Dean DC 

PROVIDER: S-EPMC6190835 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature