Introduction and geographic availability of new antibiotics approved between 1999 and 2014.

ABSTRACT:

Background

Despite the urgent need for new, effective antibiotics, few antibiotics of value have entered the market during the past decades. Therefore, incentives have been developed to stimulate antibiotic R&D. For these incentives to be effective, geographic availability for recently approved antibiotics needs to be better understood. In this study, we analyze geographic availability and market introduction of antibiotics approved between 1999 and 2014.

Material and method

We identified antibiotics, considered new chemical entities (NCEs) for systemic use approved globally between 1999 and 2014, from national medicine agencies' lists of approved drugs, and data from the WHO Collaborating Center for Drug Statistics. Geographic availability was mapped using sales data from I

SUBMITTER: Kallberg C 

PROVIDER: S-EPMC6191083 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature