De novo genome and transcriptome analyses provide insights into the biology of the trematode human parasite Fasciolopsis buski.

ABSTRACT: Many trematode parasites cause infection in humans and are thought to be a major public health problem. Their ecological diversity in different regions provides challenging questions on evolution of these organisms. In this report, we perform transcriptome analysis of the giant intestinal fluke, Fasciolopsis buski, using next generation sequencing technology. Short read sequences derived from polyA containing RNA of this organism were assembled into 30,677 unigenes that led to the annotation of 12,380 genes. Annotation of the assembled transcripts enabled insight into processes and pathways in the intestinal fluke, such as RNAi pathway and energy metabolism. The expressed kinome of the organism was characterized by identifying all protein kinases. A rough draft genome assembly for Fasciolo

SUBMITTER: Biswal DK 

PROVIDER: S-EPMC6191129 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature