Unraveling the isomeric heterogeneity of glycans: ion mobility separations in structures for lossless ion manipulations.

ABSTRACT: To address the challenges associated with glycan analyses, we have implemented a structures for lossless ion manipulations (SLIM) serpentine ultra-long path with extended routing (SUPER) ion mobility-mass spectrometry (i.e. SLIM SUPER IM-MS) platform to achieve much higher resolution of isomeric glycoforms. We have demonstrated the potential of this platform as a future component of the glycomics toolbox.

SUBMITTER: Nagy G 

PROVIDER: S-EPMC6191335 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature