Association of Nausea and Vomiting During Pregnancy With Pregnancy Loss: A Secondary Analysis of a Randomized Clinical Trial.

ABSTRACT:

Importance

Nausea and vomiting during pregnancy have been associated with a reduced risk for pregnancy loss. However, most prior studies enrolled women with clinically recognized pregnancies, thereby missing early losses.

Objective

To examine the association of nausea and vomiting during pregnancy with pregnancy loss.

Design, setting, and participants

A randomized clinical trial, Effects of Aspirin in Gestation and Reproduction, enrolled women with 1 or 2 prior pregnancy losses at 4 US clinical centers from June 15, 2007, to July 15, 2011. This secondary analysis was limited to women with a pregnancy confirmed by positive results of a human chorionic gonadotropin (hCG) test. Nausea symptoms were ascertained from daily preconception and pregnancy diaries for gestationa

SUBMITTER: Hinkle SN 

PROVIDER: S-EPMC6191846 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature