MRI Changes in the Thalamus and Basal Ganglia of Full-Term Neonates with Perinatal Asphyxia.

ABSTRACT:

Background

Magnetic resonance imaging (MRI) is the standard neuroimaging technique to assess perinatal asphyxia-associated brain injury in full-term infants. Diffusion-weighted imaging (DWI) is most informative when assessed during the first week after the insult.

Objectives

To study the DWI abnormalities of the thalamus and basal ganglia in full-term infants with perinatal asphyxia.

Methods

Fifty-five (near) term infants (normothermia n = 23; hypothermia n = 32) with thalamus and/or basal ganglia injury were included. MRI findings were assessed visually and quantitatively calculating apparent diffusion coefficient (ADC) values. Thalamus/basal ganglia ADC ratios were calculated to analyze the differences between these areas. Infants with an early MRI (days 1-3) or lat

SUBMITTER: Imai K 

PROVIDER: S-EPMC6191878 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature