High-flow nasal cannula in adults with acute respiratory failure and after extubation: a systematic review and meta-analysis.

ABSTRACT:

Background

High-flow nasal cannula (HFNC) can be used as an initial support strategy for patients with acute respiratory failure (ARF) and after extubation. However, no clear evidence exists to support or oppose HFNC use in clinical practice. We summarized the effects of HFNC, compared to conventional oxygen therapy (COT) and noninvasive ventilation (NIV), on important outcomes including treatment failure and intubation/reintubation rates in adult patients with ARF and after extubation.

Methods

We searched 4 electronic databases (Pubmed, EMBASE, Scopus, and Web of Science) to identify randomized controlled trials (RCTs) comparing the effects of HFNC with either COT or NIV on rates of 1) treatment failure and 2) intubation/reintubation in adult critically ill patients.

Res

SUBMITTER: Xu Z 

PROVIDER: S-EPMC6192218 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature