Development of a standardised set of metrics for monitoring site performance in multicentre randomised trials: a Delphi study.

ABSTRACT:

Background

Site performance is key to the success of large multicentre randomised trials. A standardised set of clear and accessible summaries of site performance could facilitate the timely identification and resolution of potential problems, minimising their impact. The aim of this study was to identify and agree a core set of key performance metrics for managing multicentre randomised trials.

Methods

We used a mixed methods approach to identify potential metrics and to achieve consensus about the final set, adapting methods that are recommended by the COMET Initiative for developing core outcome sets in health care. We used performance metrics identified from our systematic search and focus groups to create an online Delphi survey. We invited respondents to score each met

SUBMITTER: Whitham D 

PROVIDER: S-EPMC6192223 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature