Alterations of Intrinsic Connectivity Networks in Antipsychotic-Naive First-Episode Schizophrenia.

ABSTRACT:

Background

The investigation of large-scale intrinsic connectivity networks in antipsychotic-naïve first-episode schizophrenia increases our understanding of system-level cerebral dysfunction in schizophrenia while enabling control of confounding effects of medication and disease progression. Reports on functional connectivity in antipsychotic-naïve patients have been mixed and the relation between network alterations, psychopathology and cognition is unclear.

Methods

A total number of 47 patients with first-episode schizophrenia who had never received antipsychotic medication and 47 healthy controls were scanned with functional magnetic resonance imaging under resting conditions. Main outcome measures were differences in functional connectivity between groups and the relati

SUBMITTER: Anhoj S 

PROVIDER: S-EPMC6192505 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature