Chorioamnionitis as a risk factor for retinopathy of prematurity: An updated systematic review and meta-analysis.

ABSTRACT: The role of chorioamnionitis (CA) in the development of retinopathy of prematurity (ROP) is difficult to establish, because CA-exposed and CA-unexposed infants frequently present different baseline characteristics. We performed an updated systematic review and meta-analysis of studies reporting on the association between CA and ROP. We searched PubMed and EMBASE for relevant articles. Studies were included if they examined preterm or very low birth weight (VLBW, <1500g) infants and reported primary data that could be used to measure the association between exposure to CA and the presence of ROP. Of 748 potentially relevant studies, 50 studies met the inclusion criteria (38,986 infants, 9,258 CA cases). Meta-analysis showed a significant positive association between CA and any stage ROP (od

SUBMITTER: Villamor-Martinez E 

PROVIDER: S-EPMC6192636 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature