Prognoses and Clinical Outcomes of Primary and Recurrent Uveal Melanoma.

ABSTRACT:

Purpose

Uveal melanoma has a very poor prognosis despite successful local primary tumor treatment. In this study, we investigated prognostic factors that more accurately reflected the likelihood ofrecurrence and survival and delineated a prognostic model that could effectively identify different risk groups based on initial clinical parameters.

Materials and methods

Prognostic factors associated with distant recurrence, recurrence-free survival (RFS), progression-free survival, and overall survival from distant recurrence to death (OS2) were analyzed in 226 patients with stage I-III uveal melanoma who underwent primary local therapy.

Results

Forty-nine patients (21.7%) had distant recurrences, which occurred most frequently in the liver (87.7%). In a multivariate anal

SUBMITTER: Kim JH 

PROVIDER: S-EPMC6192910 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature