Ontology highlight
ABSTRACT:
SUBMITTER: Arevalo-Martin A
PROVIDER: S-EPMC6193075 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Frontiers in immunology 20181011
Spinal cord injury (SCI) results in long-term neurological and systemic consequences, including antibody-mediated autoimmunity, which has been related to impaired functional recovery. Here we show that autoantibodies that increase at the subacute phase of human SCI, 1 month after lesion, are already present in healthy subjects and directed against non-native proteins rarely present in the normal spinal cord. The increase of these autoantibodies is a fast phenomenon-their levels are already eleva ...[more]