Rapid Continuous Ruthenium-Catalysed Transfer Hydrogenation of Aromatic Nitriles to Primary Amines

ABSTRACT: A continuous flow method for the selective reduction of aromatic nitriles to the corresponding amine is reported. The method is based on a ruthenium-catalysed transfer-hydrogenation process, requires no additives, and uses isopropanol as both solvent and reducing agent. The process utilizes 1 mol% of the commercially available [Ru(

SUBMITTER: Labes R 

PROVIDER: S-EPMC6193226 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature