Associations between Maternal Water Consumption and Birth Defects in the National Birth Defects Prevention Study (2000-2005).

ABSTRACT:

Background

Water and water-based beverages constitute a major part of daily fluid intake for pregnant women, yet few epidemiologic studies have investigated the role of water consumption on birth outcomes.

Methods

We used data from the National Birth Defects Prevention Study to conduct a case-control study investigating associations between maternal water consumption during pregnancy and birth defects (BD). We used interview data on water consumption during the first trimester of pregnancy in 14,454 cases (major BDs n ≥ 50) and 5,063 controls. Total water consumption was analyzed as a continuous variable and in quartiles. We evaluated the role of dietary quality and sugar sweetened beverage consumption. Logistic regression models were used to assess effects of water consumpt

SUBMITTER: Alman BL 

PROVIDER: S-EPMC6193258 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature